7+3 Regimen

• “7” – refers to Cytarabine (Ara-C) given daily for 7 days
• “3” – refers to Anthracycline (typically daunorubicin or idarubicin) given daily for 3 days

Indications :

Contraindications:

Dosing :

• Typically, daunorubicin and cytarabine are both started on the same day. Daunorubicin ends when the third dose is given on Day 3. Cytarabine is infused continuously for 168 hours (Days 1 through 7).
• Daunorubicin is an intravenous infusion (I.V.) given over three hours once daily on Days 1, 2, and 3
• Cytarabine is given continuous I.V. over 24 hours on Days 1, 2, 3, 4, 5, 6, and 7

MoA :

Pharmacokinetics :

Toxicities/Monitoring :

• Antimicrobial ppx os typical

References:

• https://www.chemoexperts.com/7-3-daunorubicin-cytarabine/
• https://www.wikidoc.org/index.php/7%2B3_regimen