Cystitis

#med #disease #y2023 #gu

Presentation :

Uncomplicated:
- Preferred agents include nitrofurantoin (5 days), trimethoprim-sulfamethoxazole (3 days), and fosfomycin (1 dose, but expensive and possibly less effective).
- Fluoroquinolones (3 days) and β-lactam agents (including amoxicillin-clavulanate, cefdinir, cefaclor, and cefpodoxime-proxetil x3-7 days) are considered acceptable alternative second-line therapies.
  - β-Lactams are not preferred if other recommended agents are available because they are less effective in eradicating infection
- During pregnancy, the safest antibiotics are amoxicillin-clavulanate, cephalosporins, and nitrofurantoin (avoid in first trimester and near term); fluoroquinolones are contraindicated, and trimethoprim-sulfamethoxazole can only be used safely during the second trimester.