Parathyroid Carcinoma

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Presentation :

• Very rare
• Symptoms of severe hypercalcemia, with serum levels greater than 14 mg/dL (3.5 mmol/L) and markedly high PTH concentrations.

Pathophysiology :

Diagnostic Testing:

Treatment :

• Primary treatment is surgical resection.
  • Following surgery, 50% of patients may have residual or recurrent disease.
• Severe hypercalcemia that is not amenable/responsive to surgery can be treated chronically with Cinacalcet.

Prognosis:

References: